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hcc1937 breast cancer cell lines  (ATCC)


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    Structured Review

    ATCC hcc1937 breast cancer cell lines
    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, <t>HCC1937,</t> and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
    Hcc1937 Breast Cancer Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1232 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hcc1937 breast cancer cell lines/product/ATCC
    Average 97 stars, based on 1232 article reviews
    hcc1937 breast cancer cell lines - by Bioz Stars, 2026-06
    97/100 stars

    Images

    1) Product Images from "S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability"

    Article Title: S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability

    Journal: bioRxiv

    doi: 10.64898/2026.04.28.721439

    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, HCC1937, and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
    Figure Legend Snippet: A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, HCC1937, and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.

    Techniques Used:



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    ATCC hcc1937 breast cancer cell lines
    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, <t>HCC1937,</t> and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
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    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, <t>HCC1937,</t> and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
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    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, <t>HCC1937,</t> and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
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    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, <t>HCC1937,</t> and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.
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    ATCC hcc1937 breast cancer cell line
    Percent of cell proliferation of <t>HCC1937</t> ​cell line exposed to (a) PCX (5, 10, 20, 50, or 100 ​nM), and (b) CLAV (0.1, 0.5, 1, 10, 100, or 250 ​μM). Each bar represents the mean ​± ​standard error of two independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01, and ∗∗∗∗p ​< ​0.0001 vs VEH) according to one-way ANOVA followed by post-hoc Tukey's test.
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    European Collection of Authenticated Cell Cultures breast cancer cell lines hcc1937
    Percent of cell proliferation of <t>HCC1937</t> ​cell line exposed to (a) PCX (5, 10, 20, 50, or 100 ​nM), and (b) CLAV (0.1, 0.5, 1, 10, 100, or 250 ​μM). Each bar represents the mean ​± ​standard error of two independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01, and ∗∗∗∗p ​< ​0.0001 vs VEH) according to one-way ANOVA followed by post-hoc Tukey's test.
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    Image Search Results


    A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, HCC1937, and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.

    Journal: bioRxiv

    Article Title: S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability

    doi: 10.64898/2026.04.28.721439

    Figure Lengend Snippet: A) Scheme of treatment used in the experiment. B, C, D) Treatment of MDA-MB-231, HCC1937, and MCF7 cells with Olaparib and PF4708671 (PF47) alone or with PF47 pretreatment followed by olaparib treatment (PF + Ola). The PF47 dose used for all cells was 20 µM for 24 hours. The olaparib dose used for MDA-MB-231 and HCC1937 was 80 µM, and for MCF7 it was 160 µM for 6 days. Two-way ANOVA with Dunnett’s post-hoc test was used for statistical analysis and results are presented as mean ± SD of 3 biological replicates. **=p<0.01; ***=p<00.1; ****=p<000.1.

    Article Snippet: MCF7, MDA-MB-231 and HCC1937 breast cancer cell lines were originally obtained from the ATCC and were a gift from Prof. Sandra Martha Gomes Dias.

    Techniques:

    Percent of cell proliferation of HCC1937 ​cell line exposed to (a) PCX (5, 10, 20, 50, or 100 ​nM), and (b) CLAV (0.1, 0.5, 1, 10, 100, or 250 ​μM). Each bar represents the mean ​± ​standard error of two independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01, and ∗∗∗∗p ​< ​0.0001 vs VEH) according to one-way ANOVA followed by post-hoc Tukey's test.

    Journal: Neurotherapeutics

    Article Title: Clavulanic acid prevents paclitaxel-induced neuropathic pain through a systemic and central anti-inflammatory effect in mice

    doi: 10.1016/j.neurot.2024.e00522

    Figure Lengend Snippet: Percent of cell proliferation of HCC1937 ​cell line exposed to (a) PCX (5, 10, 20, 50, or 100 ​nM), and (b) CLAV (0.1, 0.5, 1, 10, 100, or 250 ​μM). Each bar represents the mean ​± ​standard error of two independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01, and ∗∗∗∗p ​< ​0.0001 vs VEH) according to one-way ANOVA followed by post-hoc Tukey's test.

    Article Snippet: The HCC1937 breast cancer cell line was obtained from the ATCC cell bank (Manassas, VA, USA).

    Techniques:

    Percent of cell proliferation of HCC1937 ​cell line exposed to CLAV (1, 10, 50, or 100 ​μM) in absence or in the presence of PCX (5 ​nM) for 48 ​h. The effect of PCX (5 ​nM) alone was also showed. Each bar represents the mean ​± ​standard error of three independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01 vs VEH) according to one-way ANOVA followed by Tukey's post hoc test.

    Journal: Neurotherapeutics

    Article Title: Clavulanic acid prevents paclitaxel-induced neuropathic pain through a systemic and central anti-inflammatory effect in mice

    doi: 10.1016/j.neurot.2024.e00522

    Figure Lengend Snippet: Percent of cell proliferation of HCC1937 ​cell line exposed to CLAV (1, 10, 50, or 100 ​μM) in absence or in the presence of PCX (5 ​nM) for 48 ​h. The effect of PCX (5 ​nM) alone was also showed. Each bar represents the mean ​± ​standard error of three independent experiments. Asterisks denote significant difference (∗∗p ​< ​0.01 vs VEH) according to one-way ANOVA followed by Tukey's post hoc test.

    Article Snippet: The HCC1937 breast cancer cell line was obtained from the ATCC cell bank (Manassas, VA, USA).

    Techniques: